Pesquisa sobre:
PROTO-ONCOGENE PROTEINS C-AKT
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DeCS
Descritor
Inglês
:
Proto-Oncogene Proteins c-akt
Descritor
Espanhol
:
Proteínas Proto-Oncogénicas c-akt
Descritor
Português
:
Proteínas Proto-Oncogênicas c-akt
Sinônimos
Inglês
:
akt Proto-Oncogene Protein
c-akt Protein
Categoria:
D08.811.913.696.620.682.700.755
D12.776.476.565
D12.776.624.664.700.168
Definição
Inglês
:
A protein-serine-threonine kinase that is activated by
PHOSPHORYLATION
in response to
GROWTH
FACTORS or
INSULIN
. It plays a major role in cell
metabolism
,
growth
, and
survival
as a core component of
SIGNAL TRANSDUCTION
. Three isoforms have been described in mammalian cells.
Nota Histórica
Inglês
:
2006(1987)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
50724
Identificador Único:
D051057
Ocorrência na BVS
:
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CID-10
SciELO
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